| Name ▲ | Type Full Name | Rarity | Version | Source Full Name | Base Item |
|---|---|---|---|---|---|
| Semiautomatic Pistol of Throne's Command | Ranged Weapon 2024 | very rare | 2014 | The Book of Many Things | semiautomatic pistol|xdmg |
| Semiautomatic Pistol of Warning | Ranged Weapon 2024 | uncommon | 2024 | 2024 Dungeon Masters Guide | semiautomatic pistol|xdmg |
| Sending Stone | Wondrous Item | uncommon | 2014 | Acquisitions Incorporated | |
| Sending Stones | Wondrous Item | uncommon | 2014 | 2014 Dungeon Masters Guide | |
| Sending Stones | Wondrous Item | uncommon | 2024 | 2024 Dungeon Masters Guide | |
| Sensory Stone | Wondrous Item | uncommon | 2014 | Sigil and the Outlands | |
| Sentinel Shield | Simple Weapon 2014 | uncommon | 2014 | 2014 Dungeon Masters Guide | |
| Sentinel Shield | Simple Weapon 2014 | uncommon | 2024 | 2024 Dungeon Masters Guide | shield|xphb |
| Serpent Scale Armor | Medium Armour 2014 | uncommon | 2014 | Candlekeep Mysteries | scale mail|PHB |
| Serpent's Fang | Melee Weapon 2014 | rare | 2014 | Candlekeep Mysteries | longsword|PHB |